Weekly Research Updates & Guidance 

Please check this page regularly for guidance and research updates.

Last updated: 6/27/25

NIH General Announcements and Notices of Special Interest     

Implementation Update: Terminating or Suspending Dangerous Gain-of-Function Research in Accordance with the Executive Order on Improving the Safety and Security of Biological Research

(NOT-OD-25-127)

National Institutes of Health

The purpose of this notice is to inform the biomedical research community of the following actions NIH is taking and requiring in response to guidance received from the White House Office of Science and Technology Policy pursuant to the May 5, 2025 Executive Order on Improving the Safety and Security of Biological Research (Executive Order).

NOTICE OF CORRECTION: Eligible Individuals, Ruth L. Kirschstein Research Service Award (NRSA) Fellowships

(NOT-OD-25-126)

Office of the Director, NIH

The purpose of this notice is to correct Section III - Eligibility Information for the Ruth L. Kirschstein Research Service Award (NRSA) Fellowships PA-25-422PA-25-423PA-25-424PA-25-425PA-25-426

Notice of Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in PA-23-317, Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)

(NOT-DE-26-002)

National Institute of Dental and Craniofacial Research

This Notice announces the participation of the National Institute of Dental and Craniofacial Research (NIDCR) in the Notice of Funding Opportunity Announcement (NOFO) PA-23-317, “Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional),” effective immediately.

NIH Announces the Open Period of FY 2026 Helium-3 Requests for Medical Research

(NOT-HL-25-028)

National Heart, Lung, and Blood Institute

The purpose of this Notice is to inform the biomedical research community of the availability of forms to request Helium-3 for FY 2026 that is intended for medical research (such as hyperpolarized MRI). Requests are being accepted now through July 15, 2025.

Notice of Correction to Key Dates in PAR-25-416 "NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)"

(NOT-GM-25-020)

National Institute of General Medical Sciences

This Notice informs potential applicants of corrections to the Key Dates information listed in PAR-25-416 "NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)”. Specifically, the Advisory Council Review date and the Earliest Start Date associated with the September 25, 2025 Application Due Date were changed.

 

Notice of NIMHD Participation in PA-25-304, NIH Exploratory/Developmental ResearchProject Grant (Parent R21 Clinical Trial Not Allowed)

(NOT-MD-25-010)

National Institute on Minority Health and Health Disparities

The purpose of this Notice is to inform potential applicants that effective immediately the National Institute on Minority Health and Health Disparities (NIMHD) will participate in PA-25-304, “NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)” issued by the National Institute of Health.

NSF – National Science Foundation General Announcements 

Department of Defense (DOD)

This e-mail is to notify the research community of recently released Fiscal Year 2025 (FY25) funding announcements for Department of Defense (DOD) programs managed by the Congressionally Directed Medical Research Programs (CDMRP).

Funding announcements released:

The Toxic Exposures Research Program (TERP) released program announcements for the following funding opportunities:

  • Investigator-Initiated Research Award
  • Translational Research Partnership Award
  • Clinical Trial Partnership Award

To view the program announcements and submit a pre-application visit: 

https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=677101

BrightFocus Foundation

AMD Fast Track 2025

September 15, 2025 – Prague, Czech Republican

BrightFocus Foundation’s Age-Related Macular Degeneration (AMD) Fast Track workshop helps speed progress toward a cure for AMD by investing in promising young scientists in the field of vision research. Graduate students, postdoctoral fellows, and other early-stage scientists focused on macular degeneration research, or those who want to enter the field can take advantage of this unique opportunity to accelerate their path towards becoming an expert in this exciting field by:

  • immersing themselves in the background knowledge and latest discoveries in macular degeneration research and
  • connecting with preeminent macular degeneration scientists and fellow early-stage researchers in the U.S. and around the world.

Contact researchgrants@brightfocus.org with questions.

Glaucoma Fast Track 2025

October 8, 2025 – Atlanta, Georgia                 

BrightFocus Foundation’s Glaucoma Fast Track workshop helps speed progress toward a cure for glaucoma by investing in promising young scientists in the field of vision research. Graduate students, postdoctoral fellows, or other early-stage scientists focused on glaucoma research, or those who want to enter the field, took advantage of this unique opportunity to accelerate their path towards becoming an expert in this exciting field by:

  • immersing themselves in the background knowledge and latest discoveries in glaucoma research,
  • connecting with preeminent glaucoma experts and fellow early-stage researchers based in the U.S. and around the world, and
  • engaging in scientific debates.

Alzheimer's Fast Track 2025

November 12th-14th, 2025 – San Diego, California

Learn from experts in the field of Alzheimer’s disease and related dementias at the Alzheimer’s Fast Track workshop. Designed for graduate students, postdoctoral fellows, and other early-career scientists focused on Alzheimer’s disease research, this immersive learning experience will accelerate your knowledge, expertise, and visibility in this exciting field.

American Heart Association

AHA Predoctoral Fellowship

Proposal deadline: Wednesday, September 3, 2025
Enhances the training of promising students in pre-doctoral or clinical health professional degree training programs and who intend careers as scientists, physician-scientists or other clinician-scientists, or related careers aimed at improving global health and wellbeing.

AHA Postdoctoral Fellowship

Proposal deadline: Thursday, September 4, 2025
Enhances the training of postdoctoral applicants who are not yet independent. The applicant must be embedded in an appropriate investigative group with the mentorship, support, and relevant scientific guidance of a research mentor.

Institutional Award for Undergraduate Student Training

Proposal deadline: Wednesday, September 10, 2025
This award is made to qualified institutions that can offer a meaningful research experience that supports the AHA mission that encourages undergraduate college students from all disciplines to consider research careers.

AHA Institutional Research Enhancement Award (AIREA)

Proposal deadline: Thursday, September 11, 2025
Stimulates research at educational institutions that provide baccalaureate or advanced degrees related to scientific research training. Eligible institutions may not have been major recipients of NIH support. Awards provide funding for small-scale research projects related to cardiovascular diseases and brain health, enhancing the research environment at eligible institutions, and exposing students to research opportunities.

Career Development Award

Proposal deadline: Thursday, December 2, 2025
Supports highly promising healthcare and academic professionals in the early years of first professional appointment to assure the applicant’s future success as a research scientist in the field of cardiovascular and/or cerebrovascular disease research.

PCORI – Patient Centered Outcomes Research Institute

2025 PCORI Annual Meeting

Date:

  • Oct. 21 - 22, 2025, All Day (ET)

Location:

JW Marriott, 1331 Pennsylvania Avenue NW, Washington, DC, 20004, United States

Join us in Washington, D.C., Oct. 21-22 for the 2025 PCORI Annual Meeting, the premier event in patient-centered comparative clinical effectiveness research.

This two-day program brings together patients, caregivers and the broader healthcare community to learn about the latest findings from PCORI-funded research and research-related projects, network and share in rich discussions to advance patient-centered research.

We look forward to sharing these two incredible days with you, as we explore ways to advance toward a more patient-centered approach to health care.

Cycle 3 2025 -- Phased Large Awards for Comparative Effectiveness Research Applicant Town Hall

Date:

  • Aug. 20, 2025, 11:30 am - 1 pm (ET)

Location: Online

Join PCORI for an information-rich webinar on the Cycle 3 2025 Phased Large Awards for Comparative Effectiveness Research PCORI Funding Announcement, which seeks to fund high-quality patient-centered comparative clinical effectiveness research (CER) projects.

Register here.

Cycle 3 2025 -- Advancing the Science of Engagement in Research Applicant Town Hall

Date:

  • Aug. 22, 2025, noon - 1 pm (ET)

Location: Online

Join PCORI for an information-rich webinar on the Cycle 3 2025 Advancing the Science of Engagement in Research PCORI Funding Announcement, which seeks to fund studies that build an evidence base on engagement in research, including:

  • Measures to capture structure/context, process and outcomes of engagement in research.
  • Techniques that lead to effective engagement in research.
  • How effective engagement techniques should be modified and resourced for different contexts, settings and communities to ensure equity in engagement and research.

Register here.

Research Forrest