Weekly Research Updates & Guidance
Please check this page regularly for guidance and research updates.
Last updated: 11/25/24
NIH General Announcements and Notices of Special Interest
Updated Guidance on Salary Limitation for Grants and Cooperative Agreements
(NOT-OD-25-025)
National Institutes of Health
This notice updates the NIH policy regarding the salary limitation for NIH grants and cooperative agreement awards.
Since 1990, Congress has legislatively mandated a limitation on salary for individuals under NIH grant and cooperative agreement awards (referred to here as a grant), to Executive Level II of the Federal Executive pay scale. The mandate appears in the annual appropriation act that provides authority for NIH to incur obligations for a given Fiscal Year (FY).
Effective October 1, 2024, the HHS policy on salary rate limitation outlines that the legislative mandate limiting salary to Executive Level II, currently $221,900, applies to both:
Notice of Special Interest (NOSI): Implementation Science for Climate Change and Health
(NOT-CA-25-003)
National Cancer Institute
National Institute on Aging
National Institute of Allergy and Infectious Diseases
National Institute of Arthritis and Musculoskeletal and Skin Diseases
National Institute of Environmental Health Sciences
Eunice Kennedy Shriver National Institute of Child Health and Human Development
National Heart, Lung, and Blood Institute
National Institute of Nursing Research
John E. Fogarty International Center
National Center for Complementary and Integrative Health
Office of Disease Prevention
National Institute on Minority Health and Health Disparities
The purpose of this Notice is to inform potential applicants of the interest of the NIH Climate Change and Health Initiative (CCHI) in supporting implementation science related to climate change and health. The CCHI seeks to reduce the health threats posed by climate change across the lifespan, improve the health of people who are at increased risk from or disproportionately impacted by climate change, and build health resilience among individuals, organizations, communities, Tribal Nations, and nations around the world. This NOSI encourages applications that propose implementation studies to understand and address barriers and facilitators to the adoption, implementation, scale-up, and sustainment of effective interventions to prevent or mitigate the health effects of climate change in the United States and globally.
(NOT-GM-24-039)
National Institute of General Medical Sciences
The purpose of this Notice of Special Interest (NOSI) is to inform applicants of the topic areas for the 2025 application due date for PAR-24-040 “Modules for Enhancing Biomedical Research Workforce Training (R25 - Clinical Trial Not Allowed)”.
(NOT-MH-25-010)
National Institute of Mental Health
The purpose of this Notice of Special Interest (NOSI) is to invite competitive revision applications to support the expansion of existing projects and/or programs awarded by the National Institute of Mental Health (NIMH). The parent activity code of the existing award must be a NIMH-funded single project research activity code under which recipients can apply (e.g., R01, U01).
(NOT-OD-25-026)
National Institutes of Health
This Notice reminds the applicant and recipient community that applicants must use FORMS-I application packages for due dates on or after January 25, 2025 and must use FORMS-H application packages for due dates on or before January 24, 2025 (see NOT-OD-24-086 for details).
(NOT-OD-25-035)
National Institutes of Health
This notice serves as a reminder to the research and research training community of multiple changes affecting application and peer review processes impacting grant applications submitted for due dates on or after January 25, 2025, and on or after May 25, 2025.
(NOT-GM-25-005)
National Institute of General Medical Sciences
The National Institute of General Medical Sciences (NIGMS) will host an informational webinar to provide advice and respond to questions from prospective applicants to PA-25-168 “Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)”.
Webinar Information
Date: Thursday, December 5, 2024
Time: 1:00 pm, Eastern Daylight Time
(NOT-GM-25-009)
National Institute of General Medical Sciences
This Notice is to inform potential applicants that the National Institute of General Medical Sciences (NIGMS) will host an informational webinar to provide a program overview and respond to questions related to PAR-24-040 “Modules for Enhancing Biomedical Research Workforce Training (R25 - Independent Clinical Trial Not Allowed)."
Webinar Information
Date: Wednesday, December 4, 2024
Time: 2:00-3:30 PM Eastern Standard Time
Notice of Special Interest (NOSI): Accelerating Malaria Vaccine and Monoclonal Antibody Discovery
(NOT-AI-24-072)
National Institute of Allergy and Infectious Diseases
The purpose of this Notice of Special Interest (NOSI) is to invite applications proposing early-phase translational research to generate new malaria vaccine candidates or monoclonal antibody (mAb)-based interventions suitable for further downstream development and clinical evaluation, particularly for Plasmodium falciparum and P. vivax.
(NOT-AI-24-078)
National Institute of Allergy and Infectious Diseases
This Notice of Special Interest (NOSI) solicits research on the immunologic characterization of mice with diverse microbial experience (commonly referred to as “dirty mice”) to determine their usefulness as research tools for advancing understanding of human immune status and function during homeostasis or in infectious or immune-mediated (e.g., allergy, autoimmunity, transplant rejection) diseases.
(NOT-AI-24-081)
National Institute of Allergy and Infectious Diseases
The objective of this Notice of Special Interest (NOSI) is to support research that contributes to the areas of interest outlined in NIAID’s Strategic Plan for the Development of a Universal Influenza Vaccine. The proposed research should have clear relevance to the research objectives defined in the strategic plan, which encompasses three major research areas:
Improve understanding of transmission, natural history and pathogenesis of influenza virus infection.
Characterize influenza immunity and correlates of immune protection.
Support rational design of universal influenza vaccines.
NSF – National Science Foundation General Announcements
Webinars and Virtual Office Hours September 16 - November 25, 2024 (STEM Ed IPRF 23-544)
Monday, November 25, 2024, 1:00 p.m. – 2:00 p.m.
The Directorate for STEM Education at the National Science Foundation is hosting a series of virtual office hours for the STEM Education Individual Postdoctoral Research Fellowships program (solicitation NSF 23-544) to support PIs in preparing proposals for the upcoming deadline. These sessions are designed to complement the Program's recorded presentations.
The office hour sessions are an opportunity to communicate with NSF program directors via videoconference. Webinars will provide an overview of the program and the solicitation that supports awards for individual postdoctoral scholars. Office hours are designed as drop-in sessions for individuals who have questions about the program or the process of preparing proposals. You may also send questions to STEMEdPRF@nsf.gov.
Zoom Videoconference Information for all sessions is:
Join ZoomGov Meeting
https://nsf.zoomgov.com/j/1606972157?pwd=yhalpOGiiJvzJBoQOf3OWllxYxvim7.1
Emerging Mathematics in Biology Webinar
Monday, November 25, 2024, 1:00 p.m. – 2:00 p.m.
Join program leaders from the U.S. National Science Foundation to learn about a funding opportunity in the Emerging Mathematics in Biology (eMB) program for the upcoming Fiscal Year 2025 competition. The eMB program aims to support research that addresses challenging and significant biological questions through novel applications of mathematical tools and methods. The eMB funding solicitation (NSF 25-509) aims to encourage new collaborations between mathematical, computer and biological scientists as well as to support innovative research activities by existing teams of researchers from mathematical and biological sciences.
This event will occur via Zoom on Monday Nov. 25, 2024 from 1 - 2 p.m. Eastern time.
Advance registration is required:
Human Networks and Data Science Program Office Hour
Monday, November 25, 2024, 3:00 p.m. – 4:00 p.m.
Please join the Human Networks and Data Science Program to discuss questions about the program with the program director.
Office hours take place over Zoom, generally on Thursdays. Please see date(s) listed below and note that times listed are in the Eastern time zone.
To join, use this link
https://nsf.zoomgov.com/j/1607898219?pwd=0Q5gFA5qfLya9KaeVi1tetoaJ05cQr.1
Wednesday, November 27, 2024, 3:00 p.m. – 4:00 p.m.
Heard about NSF Growing Access for Nationally Transformative Equity and Diversity (GRANTED) Initiative and want to learn more? Thinking of submitting a proposal to Program Description (NSF 23-221Y) or Dear Colleague Letter (NSF 23-152)? Then we invite you to GRANTED office hours, held every Wednesday from 3-4PM EDT to meet with the GRANTED team of Program Directors. If you need special accommodations to attend these meeting, please contact Dina Stroud in advance.
Join ZoomGov Meeting, by clicking here
Department of Defense (DOD)
Fiscal Year 2025 (FY25) pre-announcement for Department of Defense (DOD) programs managed by the Congressionally Directed Medical Research Programs (CDMRP).
The FY25 Defense Appropriations Bill has not been signed into law. The CDMRP is unable to release new funding opportunities under the current Continuing Resolution. The CDMRP is providing pre-announcement information to allow investigators time to plan and develop ideas for submission to anticipated funding opportunities should CDMRP receive FY25 appropriations. Pre-announcements should not be construed as an obligation or promise by the government. Once funding is available, CDMRP funding opportunities will be posted on the Grants.gov website. Pre-application and application deadlines will be available when opportunities are released, contingent upon future funding.
FY25 Pre-announcement released:
The Breast Cancer Research Program (BCRP) released a pre-announcement for the following funding opportunities:
- Breakthrough Award Levels 1 and 2
- Breakthrough Award Level 3
- Breakthrough Award Level 4
- Clinical Research Extension Award
- Era of Hope Scholar Award
- Transformative Breast Cancer Consortium Award
- Transformative Breast Cancer Consortium Development Award
To view the pre-announcement visit https://cdmrp.health.mil/pubs/press/2025/25bcrppreann)
The Peer Reviewed Alzheimer’s Research Program (PRARP) released a pre-announcement for the following funding opportunities:
- Transforming Care Award
- Transforming Diagnosis Award
- Transforming Research Award
To view the pre-announcement visit https://cdmrp.health.mil/pubs/press/2025/25prarppreann)
BrightFocus Foundation
American Heart Association
Career Development Award
Proposal deadline: Wednesday, December 5, 2024
Supports highly promising healthcare and academic professionals in the early years of first professional appointment to assure the applicant’s future success as a research scientist in the field of cardiovascular and/or cerebrovascular disease research.
Research Supplement to Promote Diversity in Science
Proposal deadline: Thursday, February 6, 2025
To enable current AHA awardees to identify and serve as mentors for predoctoral and postdoctoral fellows from underrepresented groups in science and medicine.
Transformational Project Award
Thursday, February 13, 2025
Supports highly innovative, high-impact projects that build on work in progress that could ultimately lead to critical discoveries or major advancements that will accelerate the field of cardiovascular and/or cerebrovascular research. Research deemed innovative may be built around an emerging paradigm, approaching an existing problem from a new perspective, or exhibit other uniquely creative qualities.
PCORI – Patient Centered Outcomes Research Institute
Access the 2024 PCORI Annual Meeting Anytime, Anywhere
Dive into groundbreaking discussions from the nation's leading forum on patient-centered comparative clinical effectiveness research (CER), now available for viewing at your convenience. Every session from this event is just a click away.
The complete video library showcases:
- Emerging trends shaping the future of patient-centered CER.
- Innovative approaches to advance health equity.
- Pathways to promote youth mental wellness, hepatitis C care and more.
Virtual Applicant Town Halls for Upcoming Research Funding Opportunities That Open on Dec. 3
On Dec. 3, PCORI will start accepting Letters of Intent (LOIs) for several PCORI Funding Announcements (PFAs).
These PFAs seek to fund studies addressing patient-centered comparative clinical effectiveness research (CER), studies addressing high-priority methodological gaps in patient-centered CER or studies that build an evidence base on engagement in research.
To ensure your LOI submission is fully responsive to the PFA, explore our applicant resources, which include:
- PCORI's National Priorities for Health.
- Research Project Agenda Topic Themes.
- Foundational Expectations for Partnerships in Research.
- Special Areas of Emphasis found in many of the PFAs.
You’re Invited To Attend Upcoming Town Halls
We are hosting Applicant Town Halls for several upcoming PCORI Funding Announcements (PFAs), and you are invited to register!
These Town Halls provide an in-depth look at specific funding opportunities seeking to fund studies addressing patient-centered comparative clinical effectiveness research (CER), high-priority methodological gaps in patient-centered CER or studies that build an evidence base on engagement in research.
By attending, you’ll strengthen your understanding of the critical information you may need to submit a responsive Letter of Intent (LOI), the first step in applying for PCORI funding.
Register today to learn more about the upcoming PFAs, discover resources to help you with your LOI submission and get answers to your most pressing questions.
