Weekly Research Updates & Guidance
Please check this page regularly for guidance and research updates.
Last updated: 11/17/25
NIH General Announcements and Notices of Special Interest
Interim Guidance on Reopening of NIH Extramural Activities
(NOT-OD-26-005)
National Institutes of Health
NIH is working to reestablish dates for grant and contract submissions, determine how to communicate details related to missed review meetings, reschedule dates for training, and other activities that were scheduled to occur during and immediately following the period of the government shutdown.
As of today, we can confirm that we will be rescheduling all October and November grant application submission deadlines (specific dates to be announced in a future Notice). By delaying due dates that occurred both during the lapse in funding and in the week following, applicants will have access to NIH staff and the help desks as they develop their applications.
Peer review meetings that were scheduled to take place between October 1 and November 14 have been cancelled and will be rescheduled, details to come. Additionally, council meetings that were scheduled to take place between October 1 and November 14 were cancelled and will be rescheduled, details to come.
During the shutdown, the eRA system remained open and available to accept application submissions. As such, eRA is currently reviewing service desk ticket requests from entities and individuals that needed assistance with login and passwords. eRA staff will address the tickets on a first come, first serve basis. Please note that due to the volume the response time may be longer than usual.
The eRA system was also available for recipients to submit Research Performance and Progress Reports, Federal Financial Reports, etc. The email reminders and submission confirmations were held and will be sent out in the coming weeks. If you submitted any reports during this time, no additional action is required unless you are contacted by NIH staff.
NIH will provide additional information, including a Notice on NIH operations during a continuing resolution, as soon as it is available.
Update: Recission Notice re: Implementation of NIH Research Security Policies
(NOT-OD-25-161)
National Institutes of Health
In an effort to harmonize with other Federal research agencies, NIH continues to work with the National Science Foundation and other Federal research agencies to finalize guidance on each of the required elements outlined in the Office of Science and Technology Policy Guidelines for Research Security Programs at Covered Institutions, and to develop a centralized process for recipients to certify compliance. Therefore, an implementation date for the requirements announced in NOT-OD-25-154 have not been finalized, and as such the notice is rescinded. NIH will issue updated guidance on Research Security requirements in the coming months.
Information for the NIH Extramural Community During the Lapse of Federal Government Funding
(NOT-OD-26-004)
National Institutes of Health
As you may be aware, there has been a lapse in appropriated federal fund as of October 1, 2025. Because a funding lapse has occurred, please be advised that National Institutes of Health (NIH) staff may not be available to provide normal oversight and administrative support services.
For awards received prior to the lapse in funding, you may be able to continue drawing funds from prior awards during an appropriations lapse. HHS’s Payment Management System will remain operational to continue processing those drawdown requests. The robust internal controls that currently exist will continue to ensure the integrity of grant drawdown requests and payments. Please note, if you received your notice of grant award with restrictive terms and conditions, or if your drawdown request triggers one of the Payment Management System edit checks and/or the drawdown limit controls, you may not be able to drawdown funds.
Please check our website at www.grants.nih.gov and www.HHS.gov for updates. Thank you for your assistance during this period of government shutdown and your ongoing support of NIH
NSF – National Science Foundation General Announcements
Department of Defense (DOD)
BrightFocus Foundation
November 12th-14th, 2025 – San Diego, California
Learn from experts in the field of Alzheimer’s disease and related dementias at the Alzheimer’s Fast Track workshop. Designed for graduate students, postdoctoral fellows, and other early-career scientists focused on Alzheimer’s disease research, this immersive learning experience will accelerate your knowledge, expertise, and visibility in this exciting field.
American Heart Association
Proposal deadline: Thursday, December 2, 2025
Supports highly promising healthcare and academic professionals in the early years of first professional appointment to assure the applicant’s future success as a research scientist in the field of cardiovascular and/or cerebrovascular disease research.
PCORI – Patient Centered Outcomes Research Institute
